pentobarbital will lower the extent or outcome of ethotoin by influencing hepatic enzyme CYP2C9/10 metabolism. Use Warning/Watch.pentobarbital decreases effects of sufentanil SL by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. Coadministration of CYP3A4 inducers may well minimize sufentanil amounts and ef